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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c3f6cf339aee5f79bc635f2aa009b50c5a4a218deb910d9a978dac0c30c28c9' 
  AND token = 'bHPip3So6p2pLdkUlPdY2AhpvD5nRdKulGnjECmg08k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}