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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c76ee52ce7299d0d61207524b04dc3460e385cd6ab7620dd9743895453ee074' 
  AND token = 'qz9PVa7EI2TpCYHEosqQwpUb/Hh8h/M/MPd7EUbEf80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}