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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd8385008cc265c863c18890ce86e73d8818acf53e4755d5429f32499412e5b1' 
  AND token = '54YJ37cKMCxDgSyfdTrsBrkSxTAn2IaEZrH65Mzxafo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}