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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd77ee4656713b035aa38614e5a56423d88333e358f00eb5027997c26ed18ee1c' 
  AND token = 'HpQ408OPPioS3ei+JRJIBiVvp4gZP0eEBGDR07fqZ5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}