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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d2d57c65a8c33a59a1dbb950b8c570142ebc8fc6c4b86e6b6f441168551ff3f' 
  AND token = 'I9Msq6B/oUawK4aSgpkrLY3MZg8ISNzXWEz/P1dgpRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}