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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9075a0ce8ee68ab61694971dc183486048a869a63033849f40c336723785ba7f' 
  AND token = 'Vx6MBAVeTNI8xBhm3KXSoRGFSNc673/P3LK+mJybEfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}