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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ac8f4bfd37efb084fd9827459efbd88f80d8f03fd85dfb03fe1ced10a57b66' 
  AND token = 'ahtrnIzqY3AsqD5Sv8PHygokEbq08krN5eQfAXua6v8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}