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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8474250b59fa2ec2e98aba2d64dbccaac79c1607b8352267955e3a080b44ee2' 
  AND token = 'P/CO9zQDu1UoB4bQYVENOwsO2ES9oeWhEgdvWv/YLak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}