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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e43f2125567944baa3011a4dd271d67e861631b664b278287adea1e129db43ff' 
  AND token = 'V1UP0LWIQPhxmMOEfWtg1gH4nit1K7fdoAN+PGiaQ+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}