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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f952a1b08c0d174f0508218459eceb643c1a7fe0171113354d17e686ee6c8d8' 
  AND token = '8L0dYJFmtPXMhgBP+uESALBA0CtdLwL3YQtZB3GOp+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}