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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce6cdf5956c3dcce62fee913ffa62d94425b3fc91bbe7f4aa9d0534b3332596b' 
  AND token = 'Mjcx1M4PNpXz+GhtNKPuWTU5WLqnGBvMNC+rniGJQS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}