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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66285761013635e492ee20f4fd17c1b2a2b3981f11cf4048653687f5d3b298e0' 
  AND token = '3l5Or3QBLFlTKUXuaxJV87RXb3rlujpBolMdg1+THCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}