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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff6f828ba108e9ee7fb816db9c32b3b6529d0080411ef5bcd25ffe244098ec8f' 
  AND token = 'BUQZ+7bOe5bY8EpcWuGcduiIJYrX59+mDEL1thl1sFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}