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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '266df9ff68f1e25090fc455d2672b24f2f990546e93cafce05538f5084eb2c73' 
  AND token = 'mmnLcAEc7AqHWERSou+xtcPvH2R+LNND3UsbhXyeuG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}