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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95e16da31228935dad3b9d6dc087d6c858930445c50a714d965628a6a7c90fe' 
  AND token = 'nQVFTLfH5dvHAfIR3sAq9I5siPbwW+bwBWJ05lzM/V8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}