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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49c551537d4e96ebd836876fc5fa47e77ab42938abb09e33a021a9f8b8878c32' 
  AND token = 'v0h8zeti1xEAhjRIQLgFGYi118Sl5eS13OaOqlmG0MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}