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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887da5d96f6218b64fc2783b58fc2fcf5b5839dbecdcdc4285e8355199ca7979' 
  AND token = 'EJOelMC57arQczLpIC2E/pHP+ll/v0AYKnMZSIZrlJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}