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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54341c810725bbdc5148972b1ef3bb34037594f90045ecda4a6671d966327e2c' 
  AND token = '0xu5Ft7fmI3OALIl10wt8DbjKbUerBv7XZcfhGl3q2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}