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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd18168b5635a1421262264edb92384de4ea903d30fae013a3a45c9b642fa365b' 
  AND token = 'x/BsA7u2WKk6YRMWB88AXL2Ri+M0AH54KePoV6lZ1Zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}