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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e08ed5b81c445c9660b64aaffe5998fd9fed22180ab4b37ead3a61bd4c9d6d44' 
  AND token = '0s/0QmpolaqQaVtpvAoGJ52aOr/klqHl/2fzPJpZdHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}