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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9a6aec55243cd07f9101b847e86c53e0a65ad6aa83f7efa40cef596d5793681' 
  AND token = 'obYBCN/LXAApri70z84LXYlIixznszNmHxnh1c/KdQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}