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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1db672c66de26144ad7a5751f18ab34a77e7426631f8fdc772153aa674b8ac2a' 
  AND token = 'TED7Q33fZPTBvdI316hhfVyXaZPe8+ppaxOMr44tJ/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}