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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14aabe9d10eb220cbe9bf49388bea3562b60f1c5a1fe34fa2bfa5c5f0c18c83f' 
  AND token = 'hzP4rAYOy023/oXSkySC7QaTtaMjNZ0TDT+QbS3V0yE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}