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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0cbf652c242dc78273720c7b17e1c5836380ebcbd60c4921dd5c6c7df3e074' 
  AND token = 'WxZuO7C7k9nnYYF7EaDJMfY7liPOyu7oMympO3Po4iY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}