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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52e9e7e34f1e741a2ae4bd2de8462db10e9f491f855bee9119ffb55d30b8aee6' 
  AND token = 'rt6+2Hbu/UnWaP0QnSekMKD9E2ZFU1Tvsaq8Mv2HEDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}