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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '924ab5fe9a3d95257345a9880ba57bf04bd056f28a60ec6da5190a21a60c9d6b' 
  AND token = 'ymcw4tYissawmulAHJiBJMJY8BeyQy6z5eYr9CE+l5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}