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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741dd18385c644388bfa72ca148b6b4d06cc8db5dcbbc24861620b0b7ae3d636' 
  AND token = 'Gik6HPv7l7Eh20KMDsWrmQ88TA57VnD56pKNexzMJrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}