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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ce8599481ecaf2d9c1ecd7451b551a5437e6e0e5a4e169d2468ced180500a90' 
  AND token = 'qFIDJ9XlM52HpGNEG5njgmjpITv33I8/7MpfjrXZjX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}