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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6f4726ad0dfbeb648c9f489fc3f21af69887c6bbd75e1e5d06e232b417e7d2' 
  AND token = 'x19A0CTxbh2A1eNu7YETHuAMll9Ba4S/sCd+mfeuxQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}