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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '003f778ddf6ddf299059fb0e50d8e0302ddfb9c0ce894941d505b5faa0c56658' 
  AND token = '6JMaAgyTpqGZr+Tv7+yzeH+RHJaFM0v/byzqYUGW7ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}