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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '428cd1dcd7a74fea118ae3ecb5d2cc21b97ea5b862c230a2d4e752d89bde1540' 
  AND token = 'b8LZPrw5rLzppSQp9ZWLST2eiIIYb98ySzXy9F/eaSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}