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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '496af3e2dd75ddc530faeff493ea0acd4e7a741ee35737a9d84e2f1f1fa68f3c' 
  AND token = '4YDzoYcyKr+9jrljRlV0pR5VIbM1gmxj+PS6UH38NE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}