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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1466b69b56ba233d04ca79db12a7f4a3b16fbc76b19ea6533a5b682492ae5b8f' 
  AND token = 'UpZBATybTIgXDh0DUpo331F8T+Yk8TKrUIy2n31Bwew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}