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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a7ed23b47bea758379b1f55a476ece823614594c78567f0dc1d5998c2c1f0e1' 
  AND token = 'UIh60tbJCdWvoo3FNoq/T37nXHsiZaTN07sImEY1Nho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}