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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f0d633c069fdd44b0a589d54aed6e6881083e39721557d9c29298b98a1b6fa' 
  AND token = 'grExGK7RptUtyxAnwed0Or10me79MEq9TJ46pRRA++c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}