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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d6a796596f73e9eee50f3b5a71d3112857e8a18336a7f6fa6bb5ee35ad3727' 
  AND token = 'V5nxbr7Rs+E1vLy2AWB6CqsD4CG508Ddl/R7Zq0nVtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}