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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cf84bac1cda44e9ce4d98b2780d32eba6c47e29845ebe5284a2e5d60e5e08cf' 
  AND token = 'i+rNScksRTMOLsONPBkJ7oYZ1Wrl62tNJWY1Mf7sey8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}