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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e8e98ac0ef23016e0c7f40c5646479e70d348eea4eccd7ce709f6396a20ea37' 
  AND token = 's4CCXmdMrK+kUkaUvKhNHD/kN6pX8VVXISp3Q7V24pQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}