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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c665471fa6f66f7731360b676686f4fda934f6cf007ec5d2494ef908035c231' 
  AND token = '4jHDdXEf6dX6OWfj6wTmliC9Hgw+ftNC+bmmtqxvYGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}