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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf691f0d0812828209a8dbf0fe2e57ad9aa08a410fa30332a0d649352c898cc2' 
  AND token = 'tXh/n8RxzR5M8NXFMgpd1yU9+uNdnTyG5ycd8ArPUDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}