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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '204a02e455550f3af16d4fff312cab97b219b00379c15e06aa48424d2321cbc7' 
  AND token = 'Izt1uVDoU6c9rvfM4keit3pUYfEoeKstDbFcb9bYB2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}