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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ca63905c65779be3da03e4959e4eccde71ca553e6698a9b6918df9a2ed93a20' 
  AND token = 'hhR4QdTKH+JSNU0VSpN+boKBBON0Af2IQb209QtooK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}