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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0dd7870ccf5f17637dc06062a49e7025aea5bf1217943760977843898c3b8b2' 
  AND token = 'MMUHMPXPAQIkmyiHTVqG+y6CdI++rX6nrcEiPk4DT7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}