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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5481aef46b0af6ef8fa3f03b5db4eecbc7a8737af72fa129afd0353aa1e534cc' 
  AND token = 'lAAQfetWQ+GtclxdjYoxfFq4Mc4aW/Vs3XHaAcCXtQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}