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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12043cdc59944d1e82ae58e28d94c1256d0dbad3032b9464b27ef5ff7f8aa948' 
  AND token = 'bMZF2v6zHoaQoxydTa03sPIGO9RcsgQmlO9fwVpXtew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}