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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bd1a67482c478b33c998eb74839dbda8048a3995c91c5ae5409b92878773307' 
  AND token = 'cY4Ft6FrYOweAY6x6l8vM3DTHlQEr0I5GWgEZ1wDAh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}