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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3edeecf4d8b8aa29af98ebab8c7a507bfeac2b5b2d967e60f6da96a3560a721' 
  AND token = 'fxcpRKyFtfPfDIm6IFEfOrrd0yDW7eU0W0nRmsWRMJo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}