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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f327a07be9464cf36a6b96db5f3dfb1f056171d7a777d615912f9335490bb4' 
  AND token = 'a3bxmWJZg0KwI8yZ2bbLfYBPfnsHPe85bOjdUk4o3R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}