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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1afd678f0f601c89d9a8455c3eef75e862b8464c89f2f7a81e0fd1bb748c33d' 
  AND token = 'A80iXVyjAJhU8M1ZjVdge3u7g5/qU6dSVqAw+kAGtOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}