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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad8970d1e60348852941d5e1074a60433faca23f6e51038e0d98d72f9ad3f160' 
  AND token = 'pBLtMbnB1IzTt45PyGHJZTQjnQABrkBQCvwxxtlrXOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}